Memory, Innovation, Neuroimaging and Dietary Supplements Study (MINDSS)

MINDSS is a randomized, double-blind, placebo-controlled clinical trial testing the efficacy of dietary supplements on parameters of memory & cognitive performance. The World Health Organization (WHO) have reported that there are 10 million new cases of dementia every year with a prediction to 131.5 million prevalent cases by 2050 (Alzheimer’s Disease International, 2015). These rapidly increasing numbers place a significant burden on economic, societal and health-care systems. The WHO have advocated for global action against cognitive decline, encouraging increased research into preventative therapies and improving patient care and services (WHO, 2015). Mild Cognitive Decline (MCI) is the transitional period between normal cognitive function and dementia marked by a decline in functioning greater than expected in accordance to their age and IQ and without interference to their everyday functioning (Gauthier et al., 2006). Around 5% to 20% of those suffering with MCI will go onto develop dementia (Langa & Levine, 2014) and therefore prevention and slowing of decline is critical. One easily modifiable risk factor for dementia is diet. There are several nutrients to aid healthy memory, cognition, focus and performance which have been tested in the context of clinical trials with mixed and promising results.

The primary objective of this clinical trial is to assess the effects of (i) Brain & Memory Power Boost, (ii) Brain & Body Power” and (iii) Brain & Body Power MAX versus identically matched placebos in improving parameters of memory in individuals with mild memory impairment (i.e., captured by scores between 20 and 25 on the Montreal Cognitive Assessment (MoCA) and subjective memory loss (self-report administered during the pre-screening telephone or on-line interview). Three hundred twenty healthy adults aged between 40 and 80 years of age (males and females) will be invited to participate in a 12-week study conducted at the Amen Clinics, Costa Mesa.

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